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Top journal publishes HNU research outcomes on plant protection

Updated: 2020-03-18

The thesis Molecular characterization and functional expression of voltage-gated sodium channel variants in Apolygus lucorum (Meyer-Dür) written by the research group led by Wu Shaoying, a professor at Hainan University's College of Plant Protection, has been published in Pest Management Science.

Pest Management Science is a monthly international journal that has been acting as the premier forum for papers on various aspects covering the research and technology on crop protection and pest control.

The thesis has been one of the major outcomes recently achieved by the Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests (HNU) of the Ministry of Education.

Wu's research group set insect nerve receptors as the object of study, which is the target in insects for a variety of plant- and animal-derived neurotoxins like natural pyrethroids, pyrethroid insecticides, and dichlorodiphenyltrichloroethane (DDT).

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The sodium channels existing in the nervous system of insects are important channels for nerve cells to carry electrical impulses and play an important role in the generation and transmission of action potential of endocrine cells, cardiomyocytes, skeletal muscle cells, and neurons.

Sodium channel variants of various functions are generated in the insects due to alternative splicing and RNA editing, while the mutations in sodium channels has been one of the important factors to insects developing resistance to pyrethroids, insecticides indene, and fluizone.

The research, gaining 102 sodium channel variants from apolygus lucorum, a major agricultural pest, has offered a theoretical basis for the function of sodium channel variants in regulating expression in apolygus lucorum.

In addition, the series outcomes in the research of insect toxicology by Wu's research group have been published by multiple top journals like Ecotoxicology, Bulletin of Environmental Contamination and Toxicology, as well as PLoS Neglected Tropical Diseases.